Simon Milenko has replaced David Miller in the Hurricanes' 13-man squad.
D'Arcy Short also played an important knock of 77 runs against Adelaide Strikers.
On head-to-head, the Strikers have an 8-4 lead over the Hurricanes.
Macalister Wright played a brilliant knock of 64 runs off 45 balls studded with four boundaries and three sixes
Thunder's bowling unit, which was inefficient in their previous match, will be hoping to retaliate against Hobart Hurricanes.
Matthew Wade and Co are in with a mathematical chance of qualifying for the playoffs.
In the previous encounter at Docklands, both the teams ticked the 160-run mark on the scoreboard.
David Miller's 48-ball 90 for the Hurricanes went in vain.
Hobart Hurricanes have registered three wins out of ten in the competition and have amassed just six points.
In their last meeting, the Hurricanes bowled the Sixers out for 104 while defending 129.