The duo of Rilee Russow and Khushdil Shah has been delivering impressive performances for Sultans this season.
Gladiators chased down 188 runs in the last over.
Islamabad United are currently at the top of the points table after amassing four points in three matches.
Both the teams are coming with a win from their previous game.
He has played a couple of match-winning knocks for Quetta Gladiators in PSL 2020.
Azam had previously played a brilliant knock of 59 against Islamabad United as well, and now made a good score against Gladiators.
Gladiators finished the chase in 19 overs with 5 wickets to spare. Sarfaraz Ahmed was unbeaten on 37.
Jason Roy's 57-ball 73 for the Gladiators went in vain.
On head-to-head, the Gladiators are have come out trumps in five out of eight matches.
Quetta Gladiators are currently on the second position in points table.