Dane van Niekerk has been ruled out from the remainder of the ODI series.
Sune Luus and Nadine de Klerk replaced Chole Tryon and Lizelle Lee in the squad respectively.
Find out the squads for the first ODI between South Africa Women and Windies Women.
South Africa might bring back Mignon du Preez after the batting collapse in the 2nd match.
South Africa captain Dane van Niekerk is the best option for the captain or at least vice-captain's spot.
Windies Women skipper Stephanie Taylor was terrific with the ball and picked up a 4-wicket haul.