Theunis de Bruyn struck a 38-ball 74 during the tournament opener for the Titans.
Jonathan Vandiar had a cramp while batting during the previous game that forced him to retire hurt.
Aiden Markram and JP Duminy are part of South Africa’s squad for the last two ODIs against Sri Lanka.
Markam is in great form at the moment in the domestic circuit.
Titans pair of Aiden Markram and Farhaan Behardien added 272 runs for the 6th wicket against Cape Cobras.
Hashim Amla and JP Duminy are added to the squad of Cape Cobras.
Reeza Hendricks has scored 167 runs from two matches in this tournament.
It will be very difficult for South Africa to fill the void left by AB De Villiers.
He was named in the Titans squad for the upcoming clash against the Knights in the Ram Slam T20 Clash.
"It's a massive honour for me as a young player to lead the quality players that are among the Titans squad," quoted Markram.