De Villiers smashed 176 runs off just 104 deliveries with 15 fours and 7 sixes.
It's gonna take a while for them to digest the agony caused by these defeats, but Bangladesh is a home of some spectacularly talented cricketers.
Imran remains our first-choice spinner in both the limited overs formats: Zondi
Rahim is also doubtful for the second ODI.
Here we look at all the stats and records created during the game.
Alongside the 5012 runs with the bat, Shakib Al Hasan has also bagged 224 wickets with the ball in his ODI career.
Mushfiqur displayed a lot of determination and the eagerness to make a statement. It was his valiant effort that took the team to 278/7 in their share of 50 overs.
South Africa lead the series by 1-0.
Twitter lauded the South African openers and trolled the Bangladeshi team except Mushfiqur for their poor display.
It was an utterly dominant, ruthless and prepotent display on cards from the Proteas as they ran through Bangladesh by 10 wickets.