Afghanistan registered an impressive 41-run win in the second T20I.
The Men in Blue's skipper remained unbeaten on 72 and saw his team through.
There are reports that Joe Root is determined for a comeback in the T20I team.
De Kock has previously led in a couple of ODIs and is yet to register a win as a national skipper.
Hazratullah Zazai has a T20I strike-rate of 192.85 with an average of 75.60.
When it comes to touring Pakistan, Sri Lanka have very bad memories of the same.
Kieron Pollard was the only positive for the Windies in the batting department.
Khan would need rest for at least four weeks.
He wasn't included in the T20I squad though.
Fast bowler Anrich Nortje has a shoulder injury.