In the previous encounter at Docklands, both the teams ticked the 160-run mark on the scoreboard.
Paul Stirling is the leading run-scorer of the series with 112 runs at a strike-rate of 180.64.
The successful duo of Daniel Sams and Chris Morris will be steering Thunder's bowling force.
Marcus Stoinis and Glenn Maxwell will be eager to emerge as the match-winners for Stars.
In 2019, India lost both their matches at the M Chinnaswamy Stadium, though in T20Is. On both instances, the hosts batted first.
Heat will be eager to break into the top half of the points table as they will be bolstered by the arrival of AB de Villiers in their squad.
Hobart Hurricanes have registered three wins out of ten in the competition and have amassed just six points.
Stirling grabbed the limelight in the first T20I by smashing 95 runs off just 47 balls.
Nathan Lyon has returned to the Sixers, replacing Ben Manenti.
Melbourne Stars have been in phenomenal form this season and are currently poised at the top of the table.